HCSGD entry for PCMT1
1. General information
| Official gene symbol | PCMT1 |
|---|---|
| Entrez ID | 5110 |
| Gene full name | protein-L-isoaspartate (D-aspartate) O-methyltransferase |
| Other gene symbols | PIMT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004719 | Protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | IEA TAS | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0006479 | Protein methylation | TAS | biological_process |
| GO:0030091 | Protein repair | TAS | biological_process |
| GO:0046498 | S-adenosylhomocysteine metabolic process | IEA | biological_process |
| GO:0046500 | S-adenosylmethionine metabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0341345618 | 0.9242763725 | 0.4247283962 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3312909301 |
| GSE13712_SHEAR | Up | 0.1196682962 |
| GSE13712_STATIC | Up | 0.0870857308 |
| GSE19018 | Up | 0.1124667766 |
| GSE19899_A1 | Up | 0.8842865242 |
| GSE19899_A2 | Up | 0.4413688543 |
| PubMed_21979375_A1 | Up | 0.7332646267 |
| PubMed_21979375_A2 | Up | 0.2750688374 |
| GSE35957 | Up | 0.0273448920 |
| GSE36640 | Up | 0.1695173406 |
| GSE54402 | Up | 0.2194458419 |
| GSE9593 | Up | 0.1248976904 |
| GSE43922 | Up | 0.4644607716 |
| GSE24585 | Down | -0.4174534100 |
| GSE37065 | Down | -0.0498881001 |
| GSE28863_A1 | Up | 0.0400369008 |
| GSE28863_A2 | Up | 0.7794611447 |
| GSE28863_A3 | Down | -0.4959942038 |
| GSE28863_A4 | Up | 0.0098964131 |
| GSE48662 | Down | -0.3818610180 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| S-Adenosyl-L-Homocysteine | DB01752 | EXPT02842 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031439 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037052 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038565 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
