HCSGD entry for MLXIPL

1. General information

Official gene symbolMLXIPL
Entrez ID51085
Gene full nameMLX interacting protein-like
Other gene symbolsCHREBP MIO MONDOB WBSCR14 WS-bHLH bHLHd14
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0003677DNA bindingISS NASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005634NucleusISS NAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexNAScellular_component
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008284Positive regulation of cell proliferationIMPbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0010255Glucose mediated signaling pathwayISSbiological_process
GO:0031325Positive regulation of cellular metabolic processTASbiological_process
GO:0033137Negative regulation of peptidyl-serine phosphorylationIMPbiological_process
GO:0035538Carbohydrate response element bindingTASmolecular_function
GO:0042304Regulation of fatty acid biosynthetic processTASbiological_process
GO:0042593Glucose homeostasisISSbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045723Positive regulation of fatty acid biosynthetic processISSbiological_process
GO:0045821Positive regulation of glycolysisIMPbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0046889Positive regulation of lipid biosynthetic processIMPbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0055089Fatty acid homeostasisISSbiological_process
GO:0070328Triglyceride homeostasisNASbiological_process
GO:0071157Negative regulation of cell cycle arrestIMPbiological_process
GO:0090324Negative regulation of oxidative phosphorylationIMPbiological_process
GO:2000505Regulation of energy homeostasisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63922535240.52306991760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0838602958
GSE13712_SHEARDown-0.1701481418
GSE13712_STATICDown-0.2553217428
GSE19018Up0.0056995605
GSE19899_A1Down-0.1130298043
GSE19899_A2Up0.1378731120
PubMed_21979375_A1Down-0.1658343835
PubMed_21979375_A2Down-0.5797145149
GSE35957Down-0.0385506824
GSE36640Up0.0833513294
GSE54402Up0.0343817196
GSE9593Down-0.0942994480
GSE43922Up0.0205972011
GSE24585Down-0.1483849964
GSE37065Up0.0623949185
GSE28863_A1Up0.1826681263
GSE28863_A2Up0.2862582690
GSE28863_A3Up0.2979362799
GSE28863_A4Up0.1561061784
GSE48662Up0.1241851456

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.