HCSGD entry for TXNDC12
1. General information
| Official gene symbol | TXNDC12 |
|---|---|
| Entrez ID | 51060 |
| Gene full name | thioredoxin domain containing 12 (endoplasmic reticulum) |
| Other gene symbols | AG1 AGR1 ERP16 ERP18 ERP19 PDIA16 TLP19 hAG-1 hTLP19 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0019153 | Protein-disulfide reductase (glutathione) activity | IEA | molecular_function |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0438217013 | 0.8932785722 | 0.4662210994 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1352390468 |
| GSE13712_SHEAR | Down | -0.2975140698 |
| GSE13712_STATIC | Down | -0.0710401658 |
| GSE19018 | Up | 0.3699540043 |
| GSE19899_A1 | Up | 0.9486429719 |
| GSE19899_A2 | Up | 0.4803559662 |
| PubMed_21979375_A1 | Up | 1.3166329825 |
| PubMed_21979375_A2 | Up | 0.7080498241 |
| GSE35957 | Down | -0.1828105916 |
| GSE36640 | Up | 0.0169038214 |
| GSE54402 | Down | -0.2002767474 |
| GSE9593 | Up | 0.1926748518 |
| GSE43922 | Up | 0.7284435802 |
| GSE24585 | Down | -0.0092011326 |
| GSE37065 | Up | 0.1505808634 |
| GSE28863_A1 | Down | -0.1971603109 |
| GSE28863_A2 | Up | 0.5023188703 |
| GSE28863_A3 | Down | -0.3700768221 |
| GSE28863_A4 | Down | -0.1066941680 |
| GSE48662 | Down | -0.0269536420 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001490 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
