HCSGD entry for PBX3
1. General information
| Official gene symbol | PBX3 |
|---|---|
| Entrez ID | 5090 |
| Gene full name | pre-B-cell leukemia homeobox 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002087 | Regulation of respiratory gaseous exchange by neurological system process | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007387 | Anterior compartment pattern formation | TAS | biological_process |
| GO:0007388 | Posterior compartment specification | TAS | biological_process |
| GO:0007585 | Respiratory gaseous exchange | IEA | biological_process |
| GO:0008344 | Adult locomotory behavior | IEA | biological_process |
| GO:0021516 | Dorsal spinal cord development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048666 | Neuron development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5098620797 | 0.1323273774 | 0.9999902473 | 0.7009315631 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1743338389 |
| GSE13712_SHEAR | Down | -0.2050915421 |
| GSE13712_STATIC | Down | -0.0985639620 |
| GSE19018 | Down | -0.2810616744 |
| GSE19899_A1 | Down | -0.1549578750 |
| GSE19899_A2 | Down | -1.4127509708 |
| PubMed_21979375_A1 | Up | 0.3679096763 |
| PubMed_21979375_A2 | Down | -0.3303839969 |
| GSE35957 | Down | -0.4322337274 |
| GSE36640 | Down | -0.9080940851 |
| GSE54402 | Up | 0.3147079152 |
| GSE9593 | Up | 0.2468885668 |
| GSE43922 | Down | -0.0722379275 |
| GSE24585 | Up | 0.4465283570 |
| GSE37065 | Up | 0.0606373106 |
| GSE28863_A1 | Up | 0.1784802463 |
| GSE28863_A2 | Up | 0.2156638940 |
| GSE28863_A3 | Down | -0.2606535022 |
| GSE28863_A4 | Up | 0.1115372876 |
| GSE48662 | Down | -0.0794553615 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-495-3p | MIMAT0002817 | MIRT007194 | Immunoblot//Immunohistochemistry//Luciferase reporter assay//Microarray//qRT-PCR//Western blot | Functional MTI | 23132946 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT016146 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028007 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029508 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-760 | MIMAT0004957 | MIRT036717 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
