HCSGD entry for PARD6A
1. General information
| Official gene symbol | PARD6A |
|---|---|
| Entrez ID | 50855 |
| Gene full name | par-6 partitioning defective 6 homolog alpha (C. elegans) |
| Other gene symbols | PAR-6A PAR6 PAR6C PAR6alpha TAX40 TIP-40 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0005080 | Protein kinase C binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005923 | Tight junction | ISS | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0008134 | Transcription factor binding | TAS | molecular_function |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0017048 | Rho GTPase binding | ISS | molecular_function |
| GO:0030742 | GTP-dependent protein binding | ISS | molecular_function |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0045217 | Cell-cell junction maintenance | ISS | biological_process |
| GO:0051301 | Cell division | IEA | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5611822537 | 0.4740212720 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1440817931 |
| GSE13712_SHEAR | Down | -0.6639148071 |
| GSE13712_STATIC | Down | -0.4214443684 |
| GSE19018 | Up | 0.0391278288 |
| GSE19899_A1 | Down | -0.0457437282 |
| GSE19899_A2 | Up | 0.1053221714 |
| PubMed_21979375_A1 | Up | 0.1958014388 |
| PubMed_21979375_A2 | Up | 0.1674764219 |
| GSE35957 | Up | 0.0810717673 |
| GSE36640 | Down | -0.0186339966 |
| GSE54402 | Up | 0.1040645364 |
| GSE9593 | Down | -0.1657819652 |
| GSE43922 | Up | 0.3657373606 |
| GSE24585 | Up | 0.0792494173 |
| GSE37065 | Down | -0.0282333573 |
| GSE28863_A1 | Down | -0.1488588001 |
| GSE28863_A2 | Down | -0.2143273604 |
| GSE28863_A3 | Up | 0.4320372736 |
| GSE28863_A4 | Up | 0.1532074824 |
| GSE48662 | Down | -0.0154743049 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-595 | MIMAT0003263 | MIRT006685 | qRT-PCR//Western blot | Functional MTI | 22101077 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
