HCSGD entry for TRAT1

1. General information

Official gene symbolTRAT1
Entrez ID50852
Gene full nameT cell receptor associated transmembrane adaptor 1
Other gene symbolsTCRIM TRIM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001920Negative regulation of receptor recyclingIDAbiological_process
GO:0005068Transmembrane receptor protein tyrosine kinase adaptor activityTASmolecular_function
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006968Cellular defense responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042101T cell receptor complexIDAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0050850Positive regulation of calcium-mediated signalingIDAbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0050862Positive regulation of T cell receptor signaling pathwayIDAbiological_process
GO:0051051Negative regulation of transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78782675430.74037233770.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0004864506
GSE13712_SHEARDown-0.3108241115
GSE13712_STATICDown-0.0140828329
GSE19018Up0.0173407950
GSE19899_A1Down-0.0283100528
GSE19899_A2Down-0.2639816378
PubMed_21979375_A1Up0.3848548144
PubMed_21979375_A2Up0.1520036574
GSE35957Up0.0317598211
GSE36640Down-0.0253945536
GSE54402Up0.0391926836
GSE9593Down-0.0601075950
GSE43922Up0.0296664169
GSE24585Up0.0418134583
GSE37065Down-0.0060160073
GSE28863_A1Down-0.0161136501
GSE28863_A2Up0.1466109599
GSE28863_A3Up0.1417146232
GSE28863_A4Down-0.0173006065
GSE48662Down-0.0463805662

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.