HCSGD entry for NSDHL


1. General information

Official gene symbolNSDHL
Entrez ID50814
Gene full nameNAD(P) dependent steroid dehydrogenase-like
Other gene symbolsH105E3 SDR31E1 XAP104
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001942Hair follicle developmentIEAbiological_process
GO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityIEAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005811Lipid particleIDAcellular_component
GO:0006694Steroid biosynthetic processIEAbiological_process
GO:0006695Cholesterol biosynthetic processTASbiological_process
GO:0007224Smoothened signaling pathwayIEAbiological_process
GO:0008203Cholesterol metabolic processIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0047012Sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activityIEAmolecular_function
GO:0060716Labyrinthine layer blood vessel developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00510392080.79846292310.18669722221.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7832933255
GSE13712_SHEARUp0.1956720501
GSE13712_STATICUp0.0331398480
GSE19018Down-0.4584716675
GSE19899_A1Up0.9454938261
GSE19899_A2Up1.9203400395
PubMed_21979375_A1Up0.7324976652
PubMed_21979375_A2Up1.1664408092
GSE35957Down-0.0489136309
GSE36640Up0.7459318311
GSE54402Up0.8840138345
GSE9593Up0.0605643223
GSE43922Up0.7375927492
GSE24585Down-0.7857457179
GSE37065Up0.2023421142
GSE28863_A1Down-0.0830746389
GSE28863_A2Up0.0653589472
GSE28863_A3Down-0.2180956656
GSE28863_A4Up0.0309601248
GSE48662Down-0.0595721510

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016464ProteomicsFunctional MTI (Weak)21512034
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.