HCSGD entry for RDH8
1. General information
| Official gene symbol | RDH8 |
|---|---|
| Entrez ID | 50700 |
| Gene full name | retinol dehydrogenase 8 (all-trans) |
| Other gene symbols | PRRDH SDR28C2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | IEA | molecular_function |
| GO:0004745 | Retinol dehydrogenase activity | IEA TAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006694 | Steroid biosynthetic process | TAS | biological_process |
| GO:0006703 | Estrogen biosynthetic process | IEA | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0042572 | Retinol metabolic process | IEA | biological_process |
| GO:0052650 | NADP-retinol dehydrogenase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4002731507 | 0.8725314464 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0065652053 |
| GSE13712_SHEAR | Down | -0.0992718833 |
| GSE13712_STATIC | Up | 0.1180269240 |
| GSE19018 | Up | 0.0924657443 |
| GSE19899_A1 | Up | 0.0038418217 |
| GSE19899_A2 | Down | -0.2678393963 |
| PubMed_21979375_A1 | Up | 0.2536550886 |
| PubMed_21979375_A2 | Down | -0.0283087864 |
| GSE35957 | Up | 0.0906137330 |
| GSE36640 | Up | 0.0105259521 |
| GSE54402 | Up | 0.0656955361 |
| GSE9593 | Down | -0.0498632830 |
| GSE43922 | Up | 0.0419573563 |
| GSE24585 | Up | 0.1471897873 |
| GSE37065 | Up | 0.2726400006 |
| GSE28863_A1 | Up | 0.0174414480 |
| GSE28863_A2 | Down | -0.0129557822 |
| GSE28863_A3 | Up | 0.3128649982 |
| GSE28863_A4 | Up | 0.0397297518 |
| GSE48662 | Up | 0.0682115285 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin A | DB00162 | NUTR00007 | APRD00486 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
