HCSGD entry for NEUROG3

1. General information

Official gene symbolNEUROG3
Entrez ID50674
Gene full nameneurogenin 3
Other gene symbolsAtoh5 Math4B NGN-3 bHLHa7 ngn3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001047Core promoter bindingISSmolecular_function
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0003690Double-stranded DNA bindingIEAmolecular_function
GO:0003713Transcription coactivator activityISSmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0007399Nervous system developmentTASbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0007422Peripheral nervous system developmentTASbiological_process
GO:0021510Spinal cord developmentIEAbiological_process
GO:0030855Epithelial cell differentiationIEAbiological_process
GO:0030900Forebrain developmentIEAbiological_process
GO:0030902Hindbrain developmentIEAbiological_process
GO:0031018Endocrine pancreas developmentTASbiological_process
GO:0031490Chromatin DNA bindingISSmolecular_function
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityISSbiological_process
GO:0060290TransdifferentiationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63446574220.78128771320.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0179390318
GSE13712_SHEARDown-0.0718903497
GSE13712_STATICUp0.2043785363
GSE19018Down-0.0444534493
GSE19899_A1Down-0.0027092337
GSE19899_A2Up0.0851249817
PubMed_21979375_A1Down-0.3913426905
PubMed_21979375_A2Up0.0224858581
GSE35957Up0.0401719109
GSE36640Down-0.1321801363
GSE54402Up0.0173125758
GSE9593Up0.0908200060
GSE43922Up0.0138780660
GSE24585Up0.0790485228
GSE37065Down-0.0830184173
GSE28863_A1Down-0.1185142122
GSE28863_A2Up0.2444534853
GSE28863_A3Up0.3080896576
GSE28863_A4Up0.1165025693
GSE48662Up0.0308627420

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.