HCSGD entry for ATP6V0A4

1. General information

Official gene symbolATP6V0A4
Entrez ID50617
Gene full nameATPase, H+ transporting, lysosomal V0 subunit a4
Other gene symbolsA4 ATP6N1B ATP6N2 RDRTA2 RTA1C RTADR STV1 VPH1 VPP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000220Vacuolar proton-transporting V-type ATPase, V0 domainIEAcellular_component
GO:0001503OssificationIMPbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005768EndosomeISScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0006885Regulation of pHIMPbiological_process
GO:0007588ExcretionIMPbiological_process
GO:0007605Sensory perception of soundIMPbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0010008Endosome membraneTAScellular_component
GO:0015078Hydrogen ion transmembrane transporter activityIEAmolecular_function
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0015992Proton transportIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0016471Vacuolar proton-transporting V-type ATPase complexIDAcellular_component
GO:0030670Phagocytic vesicle membraneTAScellular_component
GO:0031526Brush border membraneIDAcellular_component
GO:0033572Transferrin transportTASbiological_process
GO:0045177Apical part of cellIDAcellular_component
GO:0051117ATPase bindingIPImolecular_function
GO:0051701Interaction with hostTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15816875880.97470371570.78892550691.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0693387845
GSE13712_SHEARDown-0.0429965125
GSE13712_STATICUp0.2646223270
GSE19018Up0.1110293585
GSE19899_A1Up0.1833132360
GSE19899_A2Up0.6037243188
PubMed_21979375_A1Up0.5576908761
PubMed_21979375_A2Up0.2679626822
GSE35957Down-0.0302329085
GSE36640Up0.6336495585
GSE54402Up0.0129451493
GSE9593Down-0.0302799185
GSE43922Up0.0717357231
GSE24585Up0.0733165461
GSE37065Up0.1016516682
GSE28863_A1Down-0.0931797004
GSE28863_A2Up0.0587969846
GSE28863_A3Up0.1211593145
GSE28863_A4Up0.0412363945
GSE48662Down-0.0294800695

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.