HCSGD entry for PAFAH2
1. General information
| Official gene symbol | PAFAH2 |
|---|---|
| Entrez ID | 5051 |
| Gene full name | platelet-activating factor acetylhydrolase 2, 40kDa |
| Other gene symbols | HSD-PLA2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity | IEA | molecular_function |
| GO:0005543 | Phospholipid binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006629 | Lipid metabolic process | TAS | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1468230272 | 0.7508161962 | 0.7679906399 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1302843316 |
| GSE13712_SHEAR | Up | 0.3577602104 |
| GSE13712_STATIC | Down | -0.0678359061 |
| GSE19018 | Up | 0.1167689789 |
| GSE19899_A1 | Up | 0.0041781762 |
| GSE19899_A2 | Up | 0.3888681940 |
| PubMed_21979375_A1 | Up | 0.6806071966 |
| PubMed_21979375_A2 | Down | -0.0151547760 |
| GSE35957 | Down | -0.1379479382 |
| GSE36640 | Up | 0.9226990342 |
| GSE54402 | Down | -0.0844370125 |
| GSE9593 | Up | 0.3064519246 |
| GSE43922 | Up | 0.4786179110 |
| GSE24585 | Down | -0.1669220015 |
| GSE37065 | Down | -0.0894302107 |
| GSE28863_A1 | Down | -0.3647543316 |
| GSE28863_A2 | Up | 0.2988300284 |
| GSE28863_A3 | Down | -0.4708484715 |
| GSE28863_A4 | Down | -0.1223123426 |
| GSE48662 | Up | 0.2030310618 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019805 | Microarray | Functional MTI (Weak) | 20215506 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
