HCSGD entry for PAEP
1. General information
| Official gene symbol | PAEP |
|---|---|
| Entrez ID | 5047 |
| Gene full name | progestagen-associated endometrial protein |
| Other gene symbols | GD GdA GdF GdS PAEG PEP PP14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0036094 | Small molecule binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0578087611 | 0.9660365944 | 0.5209094798 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0056012682 |
| GSE13712_SHEAR | Up | 0.1562311632 |
| GSE13712_STATIC | Up | 0.1403675753 |
| GSE19018 | Up | 0.0540778409 |
| GSE19899_A1 | Up | 0.6897169915 |
| GSE19899_A2 | Up | 1.2591750196 |
| PubMed_21979375_A1 | Up | 0.6208191685 |
| PubMed_21979375_A2 | Up | 1.4731707155 |
| GSE35957 | Up | 0.2285409912 |
| GSE36640 | Down | -0.0785538257 |
| GSE54402 | Up | 0.1140298740 |
| GSE9593 | Up | 0.0163180957 |
| GSE43922 | Up | 0.1072374446 |
| GSE24585 | Up | 0.0282136546 |
| GSE37065 | Down | -0.1105039005 |
| GSE28863_A1 | Down | -0.0008753093 |
| GSE28863_A2 | Down | -0.0877243154 |
| GSE28863_A3 | Up | 0.1532883199 |
| GSE28863_A4 | Up | 0.0130037869 |
| GSE48662 | Down | -0.0996360001 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 12-Bromododecanoic Acid | DB02405 | EXPT00749 |
| Palmitic Acid | DB03796 | EXPT01393 | EXPT02607 |
| Glycerol | DB04077 | EXPT01027 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 9262286 | We studied the in-vitro secretory function of non-polarized and polarized cultured Fallopian tube epithelial cells by measurement of the placental protein 14 (PP14) secretion in primary cultures and subcultures from Fallopian tubes obtained from eight premenopausal women in different phases of the ovarian cycle |
| 9262286 | PP14 secretion into the culture media was measured by a radioimmunoassay using 125I-PP14 as label and rabbit anti-human PP14 serum |
| 9262286 | There was a large amount of PP14 secretion into the culture media in primary cultures, the secretion decreasing considerably after subculture 1 |
| 9262286 | PP14 secretion after subculture 2 was not different from the control values |
| 9262286 | Polarized and non-polarized cells secreted similar amounts of PP14 and frozen-thawed cells did not appear to secrete PP14 |
| 9262286 | Epithelial cells from Fallopian tubes obtained at different phases of the ovarian cycle did not appear to show any difference in PP14 secretion rates |
| 9262286 | Our data suggest that the in-vitro secretion of PP14 by human Fallopian tube epithelial cells is adversely affected by cell ageing and freezing |
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