HCSGD entry for P2RY4

1. General information

Official gene symbolP2RY4
Entrez ID5030
Gene full namepyrimidinergic receptor P2Y, G-protein coupled, 4
Other gene symbolsNRU P2P P2Y4 UNR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0015065Uridine nucleotide receptor activityTASmolecular_function
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0030321Transepithelial chloride transportIEAbiological_process
GO:0045028G-protein coupled purinergic nucleotide receptor activityIEAmolecular_function
GO:0045030UTP-activated nucleotide receptor activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51250122340.75851512100.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0804145276
GSE13712_SHEARUp0.1090002775
GSE13712_STATICDown-0.0495303012
GSE19018Down-0.1597829593
GSE19899_A1Up0.1870166701
GSE19899_A2Up0.2203465237
PubMed_21979375_A1Up0.0562096503
PubMed_21979375_A2Up0.0041543555
GSE35957Up0.1330486289
GSE36640Up0.2361283499
GSE54402Up0.0326096679
GSE9593Up0.1260484580
GSE43922Up0.0213802841
GSE24585Up0.0411577207
GSE37065Down-0.0016254838
GSE28863_A1Up0.1256634134
GSE28863_A2Down-0.0111021897
GSE28863_A3Up0.2788115472
GSE28863_A4Down-0.1159378235
GSE48662Down-0.3439357010

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.