HCSGD entry for P2RY2
1. General information
| Official gene symbol | P2RY2 |
|---|---|
| Entrez ID | 5029 |
| Gene full name | purinergic receptor P2Y, G-protein coupled, 2 |
| Other gene symbols | HP2U P2RU1 P2U P2U1 P2UR P2Y2 P2Y2R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006873 | Cellular ion homeostasis | TAS | biological_process |
| GO:0007200 | Phospholipase C-activating G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0042312 | Regulation of vasodilation | IEA | biological_process |
| GO:0045028 | G-protein coupled purinergic nucleotide receptor activity | IEA | molecular_function |
| GO:0070257 | Positive regulation of mucus secretion | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0863062422 | 0.9252802249 | 0.6166865943 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0288297473 |
| GSE13712_SHEAR | Up | 0.8403444994 |
| GSE13712_STATIC | Up | 0.3838492567 |
| GSE19018 | Up | 0.0317095209 |
| GSE19899_A1 | Down | -0.0633723856 |
| GSE19899_A2 | Up | 0.1142967516 |
| PubMed_21979375_A1 | Up | 0.6087018244 |
| PubMed_21979375_A2 | Up | 0.0507297896 |
| GSE35957 | Down | -0.1304874628 |
| GSE36640 | Up | 0.4622140102 |
| GSE54402 | Up | 0.2436990234 |
| GSE9593 | Down | -0.0657030476 |
| GSE43922 | Up | 0.0618383541 |
| GSE24585 | Up | 0.1602052177 |
| GSE37065 | Up | 0.2295566754 |
| GSE28863_A1 | Down | -0.0428371101 |
| GSE28863_A2 | Up | 0.0270282667 |
| GSE28863_A3 | Up | 0.1180376805 |
| GSE28863_A4 | Up | 0.1215204500 |
| GSE48662 | Down | -0.0587686997 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018463 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17982416 | Agonists of P2Y1 (ADP) and P2Y2/P2Y4 (ATP, UTP) receptors at 10 microM or 100 microM concentrations were added to the bathing medium |
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