HCSGD entry for OXT

1. General information

Official gene symbolOXT
Entrez ID5020
Gene full nameoxytocin/neurophysin I prepropeptide
Other gene symbolsOT OT-NPI OXT-NPI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001975Response to amphetamineIEAbiological_process
GO:0002027Regulation of heart rateIEAbiological_process
GO:0002125Maternal aggressive behaviorIEAbiological_process
GO:0005185Neurohypophyseal hormone activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0007613MemoryIEAbiological_process
GO:0007625Grooming behaviorIEAbiological_process
GO:0009744Response to sucroseIEAbiological_process
GO:0010701Positive regulation of norepinephrine secretionIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0030141Secretory granuleIEAcellular_component
GO:0030431SleepIEAbiological_process
GO:0031855Oxytocin receptor bindingIEAmolecular_function
GO:0032094Response to foodIEAbiological_process
GO:0032308Positive regulation of prostaglandin secretionIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032526Response to retinoic acidIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0034695Response to prostaglandin EIEAbiological_process
GO:0035176Social behaviorIEAbiological_process
GO:0035811Negative regulation of urine volumeIEAbiological_process
GO:0035815Positive regulation of renal sodium excretionIEAbiological_process
GO:0042220Response to cocaineIEAbiological_process
GO:0042538Hyperosmotic salinity responseIEAbiological_process
GO:0042711Maternal behaviorIEAbiological_process
GO:0042713Sperm ejaculationIEAbiological_process
GO:0042755Eating behaviorIEAbiological_process
GO:0042756Drinking behaviorIEAbiological_process
GO:0043195Terminal boutonIEAcellular_component
GO:0043434Response to peptide hormoneIEAbiological_process
GO:0045472Response to etherIEAbiological_process
GO:0045776Negative regulation of blood pressureIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0045778Positive regulation of ossificationIEAbiological_process
GO:0045925Positive regulation of female receptivityIEAbiological_process
GO:0050806Positive regulation of synaptic transmissionIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0051602Response to electrical stimulusIEAbiological_process
GO:0051930Regulation of sensory perception of painIEAbiological_process
GO:0051965Positive regulation of synapse assemblyIEAbiological_process
GO:0060179Male mating behaviorIEAbiological_process
GO:0060406Positive regulation of penile erectionIEAbiological_process
GO:0060450Positive regulation of hindgut contractionIEAbiological_process
GO:0060455Negative regulation of gastric acid secretionIEAbiological_process
GO:0070474Positive regulation of uterine smooth muscle contractionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32486628170.84499100340.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1275758963
GSE13712_SHEARUp0.0382767567
GSE13712_STATICDown-0.1777548545
GSE19018Up0.1325619761
GSE19899_A1Down-0.0658404181
GSE19899_A2Up0.0219012980
PubMed_21979375_A1Up0.3150265607
PubMed_21979375_A2Down-0.1180159807
GSE35957Up0.2452892021
GSE36640Up0.0696285292
GSE54402Down-0.0656395467
GSE9593Up0.0647679197
GSE43922Up0.0606153748
GSE24585Up0.0797532372
GSE37065Up0.0405092987
GSE28863_A1Down-0.0528938226
GSE28863_A2Up0.1690788495
GSE28863_A3Up0.5141596661
GSE28863_A4Up0.1373325325
GSE48662Up0.1806835252

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

OxytocinDB00107 BTD00016 | BIOD00016

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.