HCSGD entry for OPRK1

1. General information

Official gene symbolOPRK1
Entrez ID4986
Gene full nameopioid receptor, kappa 1
Other gene symbolsKOR OPRK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004985Opioid receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIMPcellular_component
GO:0006955Immune responseIDAbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayISSbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007600Sensory perceptionTASbiological_process
GO:0007610BehaviorTASbiological_process
GO:0007626Locomotory behaviorISSbiological_process
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0019233Sensory perception of painISSbiological_process
GO:0031635Adenylate cyclase-inhibiting opioid receptor signaling pathwayIDAbiological_process
GO:0038003Opioid receptor signaling pathwayIDAbiological_process
GO:0038048Dynorphin receptor activityIDA IEA IMPmolecular_function
GO:0046877Regulation of saliva secretionISSbiological_process
GO:0051607Defense response to virusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64443952360.82624441320.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0845757391
GSE13712_SHEARDown-0.0191887652
GSE13712_STATICUp0.1400232130
GSE19018Down-0.0009585337
GSE19899_A1Up0.1267898753
GSE19899_A2Down-0.0098747223
PubMed_21979375_A1Up0.1942524655
PubMed_21979375_A2Down-0.1077665794
GSE35957Up0.1052064557
GSE36640Up0.0495343426
GSE54402Up0.0233954109
GSE9593Down-0.1807010133
GSE43922Up0.0300269617
GSE24585Up0.0958049738
GSE37065Down-0.1463397969
GSE28863_A1Down-0.0764166333
GSE28863_A2Up0.0776940218
GSE28863_A3Up0.3141648155
GSE28863_A4Up0.0251932301
GSE48662Down-0.0310346553

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT020420MicroarrayFunctional MTI (Weak)17242205
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.