HCSGD entry for OAZ2
1. General information
| Official gene symbol | OAZ2 |
|---|---|
| Entrez ID | 4947 |
| Gene full name | ornithine decarboxylase antizyme 2 |
| Other gene symbols | AZ2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006521 | Regulation of cellular amino acid metabolic process | TAS | biological_process |
| GO:0006595 | Polyamine metabolic process | TAS | biological_process |
| GO:0008073 | Ornithine decarboxylase inhibitor activity | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6033777440 | 0.1820231032 | 0.9999902473 | 0.8270378215 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1504109901 |
| GSE13712_SHEAR | Down | -0.7759894418 |
| GSE13712_STATIC | Down | -0.4595456199 |
| GSE19018 | Up | 0.2773116626 |
| GSE19899_A1 | Down | -0.1570058811 |
| GSE19899_A2 | Up | 0.1952880591 |
| PubMed_21979375_A1 | Up | 0.2399713839 |
| PubMed_21979375_A2 | Down | -0.7950133320 |
| GSE35957 | Up | 0.3382780491 |
| GSE36640 | Up | 0.0419599819 |
| GSE54402 | Up | 0.1181735815 |
| GSE9593 | Up | 0.3028591044 |
| GSE43922 | Down | -0.3249536318 |
| GSE24585 | Down | -0.1243987591 |
| GSE37065 | Down | -0.2400677499 |
| GSE28863_A1 | Down | -0.0401754653 |
| GSE28863_A2 | Down | -0.0866478426 |
| GSE28863_A3 | Down | -0.1625545345 |
| GSE28863_A4 | Up | 0.0698842753 |
| GSE48662 | Up | 0.5110104069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Ornithine | DB00129 | NUTR00043 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029932 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046724 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
