HCSGD entry for TBC1D25
1. General information
| Official gene symbol | TBC1D25 |
|---|---|
| Entrez ID | 4943 |
| Gene full name | TBC1 domain family, member 25 |
| Other gene symbols | MG81 OATL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005776 | Autophagic vacuole | IDA | cellular_component |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0008483 | Transaminase activity | IEA | molecular_function |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0032320 | Positive regulation of Ras GTPase activity | IDA | biological_process |
| GO:0032851 | Positive regulation of Rab GTPase activity | IDA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IDA | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IDA | biological_process |
| GO:1901096 | Regulation of autophagic vacuole maturation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3351580829 | 0.7758672695 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1344904746 |
| GSE13712_SHEAR | Down | -0.0572517528 |
| GSE13712_STATIC | Down | -0.0958872512 |
| GSE19018 | Up | 0.0225253245 |
| GSE19899_A1 | Down | -0.0138448820 |
| GSE19899_A2 | Up | 0.3228371012 |
| PubMed_21979375_A1 | Up | 0.3609479800 |
| PubMed_21979375_A2 | Up | 0.3884700578 |
| GSE35957 | Down | -0.0025470731 |
| GSE36640 | Up | 0.1239474768 |
| GSE54402 | Up | 0.2225887016 |
| GSE9593 | Down | -0.1010246560 |
| GSE43922 | Up | 0.0474736180 |
| GSE24585 | Down | -0.2066378563 |
| GSE37065 | Down | -0.0092871324 |
| GSE28863_A1 | Up | 0.2809076189 |
| GSE28863_A2 | Up | 0.1804240952 |
| GSE28863_A3 | Up | 0.4231870757 |
| GSE28863_A4 | Down | -0.1282502297 |
| GSE48662 | Down | -0.2125594628 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031139 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036096 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
