HCSGD entry for NUMA1

1. General information

Official gene symbolNUMA1
Entrez ID4926
Gene full namenuclear mitotic apparatus protein 1
Other gene symbolsNUMA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000090Mitotic anaphaseTASbiological_process
GO:0000132Establishment of mitotic spindle orientationIEAbiological_process
GO:0000139Golgi membraneIEAcellular_component
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000922Spindle poleIDA IEAcellular_component
GO:0005198Structural molecule activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005694ChromosomeIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005819SpindleTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005876Spindle microtubuleTAScellular_component
GO:0006997Nucleus organizationTASbiological_process
GO:0007067MitosisIEAbiological_process
GO:0008017Microtubule bindingIEAmolecular_function
GO:0016363Nuclear matrixIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045177Apical part of cellIEAcellular_component
GO:0051321Meiotic cell cycleIEAbiological_process
GO:0060487Lung epithelial cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07989384140.72393182630.59545135901.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0338031679
GSE13712_SHEARDown-0.1590151875
GSE13712_STATICDown-0.2516873182
GSE19018Up0.2584760204
GSE19899_A1Down-0.0709830070
GSE19899_A2Down-0.0535116295
PubMed_21979375_A1Down-0.4440221475
PubMed_21979375_A2Up0.1900704515
GSE35957Down-0.1525442692
GSE36640Up0.0544578750
GSE54402Down-0.3152122260
GSE9593Down-0.0872463807
GSE43922Up0.0115100321
GSE24585Up0.5328681199
GSE37065Up0.2386219264
GSE28863_A1Up0.8696299794
GSE28863_A2Up0.6114784010
GSE28863_A3Up0.3079291065
GSE28863_A4Down-0.0559400021
GSE48662Up0.7678818878

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018163MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.