HCSGD entry for NRL

1. General information

Official gene symbolNRL
Entrez ID4901
Gene full nameneural retina leucine zipper
Other gene symbolsD14S46E NRL-MAF RP27
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007468Regulation of rhodopsin gene expressionTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0043522Leucine zipper domain bindingIPImolecular_function
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045872Positive regulation of rhodopsin gene expressionIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046548Retinal rod cell developmentIEAbiological_process
GO:0050896Response to stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45313199350.89335705330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0298273074
GSE13712_SHEARDown-0.0805951845
GSE13712_STATICUp0.0798789972
GSE19018Up0.1749315291
GSE19899_A1Up0.0482402006
GSE19899_A2Up0.0875464348
PubMed_21979375_A1Up0.1306679929
PubMed_21979375_A2Up0.1095012732
GSE35957Up0.1661655083
GSE36640Up0.0653153436
GSE54402Up0.0601189492
GSE9593Up0.0201034489
GSE43922Up0.0348162981
GSE24585Up0.2052218687
GSE37065Up0.1051351759
GSE28863_A1Down-0.3203037463
GSE28863_A2Down-0.1892233884
GSE28863_A3Up0.2035364777
GSE28863_A4Up0.1457201646
GSE48662Up0.0285179213

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.