HCSGD entry for NPTX1
1. General information
| Official gene symbol | NPTX1 |
|---|---|
| Entrez ID | 4884 |
| Gene full name | neuronal pentraxin I |
| Other gene symbols | NP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006839 | Mitochondrial transport | IEA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0030133 | Transport vesicle | IEA | cellular_component |
| GO:0035865 | Cellular response to potassium ion | IEA | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043653 | Mitochondrial fragmentation involved in apoptotic process | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060385 | Axonogenesis involved in innervation | IEA | biological_process |
| GO:0071333 | Cellular response to glucose stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1245394818 | 0.0009285513 | 0.7202455085 | 0.0573718310 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.4555061613 |
| GSE13712_SHEAR | Up | 0.0088794369 |
| GSE13712_STATIC | Up | 0.1166691623 |
| GSE19018 | Up | 0.9969980917 |
| GSE19899_A1 | Down | -2.6806904729 |
| GSE19899_A2 | Down | -1.9628601257 |
| PubMed_21979375_A1 | Down | -6.6004553901 |
| PubMed_21979375_A2 | Down | -2.2107746766 |
| GSE35957 | Down | -0.7320914300 |
| GSE36640 | Down | -4.0405263915 |
| GSE54402 | Down | -1.7831303701 |
| GSE9593 | Up | 0.3288051180 |
| GSE43922 | Down | -1.7488358900 |
| GSE24585 | Up | 0.1079794929 |
| GSE37065 | Down | -0.0796289901 |
| GSE28863_A1 | Down | -0.0173370494 |
| GSE28863_A2 | Up | 0.3360550697 |
| GSE28863_A3 | Up | 0.3897188114 |
| GSE28863_A4 | Up | 0.0115307689 |
| GSE48662 | Up | 0.1231457847 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT001930 | Luciferase reporter assay | Functional MTI | 18539147 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT001930 | immunoprecipitaion//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-760 | MIMAT0004957 | MIRT036754 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040023 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047499 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047746 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051875 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052609 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
