HCSGD entry for NOP2
1. General information
| Official gene symbol | NOP2 |
|---|---|
| Entrez ID | 4839 |
| Gene full name | NOP2 nucleolar protein |
| Other gene symbols | NOL1 NOP120 NSUN1 p120 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006364 | RRNA processing | IEA | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0330849322 | 0.1538585084 | 0.4186675481 | 0.7575214740 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4525158539 |
| GSE13712_SHEAR | Up | 0.5233943020 |
| GSE13712_STATIC | Up | 0.2799644878 |
| GSE19018 | Down | -0.7532976582 |
| GSE19899_A1 | Up | 0.1710460580 |
| GSE19899_A2 | Up | 0.8859749759 |
| PubMed_21979375_A1 | Up | 1.4231274896 |
| PubMed_21979375_A2 | Up | 1.5188429896 |
| GSE35957 | Down | -0.2775199276 |
| GSE36640 | Down | -0.3913849691 |
| GSE54402 | Up | 0.5909740124 |
| GSE9593 | Down | -0.5304951490 |
| GSE43922 | Up | 0.4632537007 |
| GSE24585 | Down | -0.7587996452 |
| GSE37065 | Down | -0.1170838012 |
| GSE28863_A1 | Down | -0.4766782748 |
| GSE28863_A2 | Down | -0.0081665887 |
| GSE28863_A3 | Down | -0.4565264136 |
| GSE28863_A4 | Up | 0.1823273935 |
| GSE48662 | Down | -0.2754375177 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022000 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027322 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029532 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036055 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036456 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-935 | MIMAT0004978 | MIRT036665 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037432 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038501 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040113 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043501 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043682 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044113 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047626 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048389 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051348 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
