HCSGD entry for NHP2L1
1. General information
| Official gene symbol | NHP2L1 |
|---|---|
| Entrez ID | 4809 |
| Gene full name | NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) |
| Other gene symbols | 15.5K FA-1 FA1 NHPX OTK27 SNRNP15-5 SNU13 SPAG12 SSFA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003723 | RNA binding | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA TAS | cellular_component |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030515 | SnoRNA binding | IDA | molecular_function |
| GO:0030529 | Ribonucleoprotein complex | IEA | cellular_component |
| GO:0031428 | Box C/D snoRNP complex | NAS | cellular_component |
| GO:0042254 | Ribosome biogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6397233122 | 0.7998655826 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3424960564 |
| GSE13712_SHEAR | Down | -0.1170793019 |
| GSE13712_STATIC | Down | -0.0605802426 |
| GSE19018 | Down | -0.1956678097 |
| GSE19899_A1 | Down | -0.0441122845 |
| GSE19899_A2 | Up | 0.2421546745 |
| PubMed_21979375_A1 | Up | 0.4381891355 |
| PubMed_21979375_A2 | Down | -0.1223011547 |
| GSE35957 | Down | -0.0468139077 |
| GSE36640 | Down | -0.2851471772 |
| GSE54402 | Up | 0.2262773372 |
| GSE9593 | Up | 0.1065332294 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0142867514 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Alpha-Hydroxy-Beta-Phenyl-Propionic Acid | DB02494 | EXPT01733 |
| Anisomycin | DB07374 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046317 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049439 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
