HCSGD entry for NHLH2

1. General information

Official gene symbolNHLH2
Entrez ID4808
Gene full namenescient helix loop helix 2
Other gene symbolsHEN2 NSCL2 bHLHa34
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001102RNA polymerase II activating transcription factor bindingIPImolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0007617Mating behaviorIEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0042698Ovulation cycleIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61948267160.85290135630.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0533464791
GSE13712_SHEARDown-0.0221178099
GSE13712_STATICUp0.0734141756
GSE19018Down-0.0537005325
GSE19899_A1Up0.0366661642
GSE19899_A2Up0.1578809359
PubMed_21979375_A1Up0.6479619440
PubMed_21979375_A2Down-0.1199202611
GSE35957Up0.1225269971
GSE36640Up0.0145742133
GSE54402Down-0.0383055109
GSE9593Down-0.0681644566
GSE43922Up0.0533037156
GSE24585Up0.0559852264
GSE37065Down-0.0368784719
GSE28863_A1Down-0.0994018224
GSE28863_A2Up0.2124853357
GSE28863_A3Up0.1370821653
GSE28863_A4Up0.0309014727
GSE48662Down-0.0414685734

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.