HCSGD entry for NFX1
1. General information
| Official gene symbol | NFX1 |
|---|---|
| Entrez ID | 4799 |
| Gene full name | nuclear transcription factor, X-box binding 1 |
| Other gene symbols | NFX2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0045347 | Negative regulation of MHC class II biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8725523802 | 0.2512752897 | 0.9999902473 | 0.9627098836 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0339582005 |
| GSE13712_SHEAR | Down | -0.0506682567 |
| GSE13712_STATIC | Up | 0.0361553167 |
| GSE19018 | Down | -0.1347808419 |
| GSE19899_A1 | Down | -0.1284924491 |
| GSE19899_A2 | Down | -0.1581023537 |
| PubMed_21979375_A1 | Down | -0.4073403403 |
| PubMed_21979375_A2 | Up | 0.1326981613 |
| GSE35957 | Down | -0.2018401719 |
| GSE36640 | Down | -0.1053610171 |
| GSE54402 | Down | -0.2334491450 |
| GSE9593 | Up | 0.2372430876 |
| GSE43922 | Down | -0.2723901333 |
| GSE24585 | Up | 0.0191664806 |
| GSE37065 | Up | 0.0373815065 |
| GSE28863_A1 | Up | 0.2130943289 |
| GSE28863_A2 | Up | 0.0321558202 |
| GSE28863_A3 | Down | -0.7572420614 |
| GSE28863_A4 | Up | 0.0756058527 |
| GSE48662 | Up | 0.2007850406 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20943973 | NFX1-123, the longer splice variant of NFX1, interacts with HPV16 E6, as well as cytoplasmic poly(A) binding proteins 1 and 4 (PABPC1 and PABPC4) |
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