HCSGD entry for NEDD9
1. General information
| Official gene symbol | NEDD9 |
|---|---|
| Entrez ID | 4739 |
| Gene full name | neural precursor cell expressed, developmentally down-regulated 9 |
| Other gene symbols | CAS-L CAS2 CASL CASS2 HEF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000922 | Spindle pole | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005819 | Spindle | TAS | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007010 | Cytoskeleton organization | NAS | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | NAS | biological_process |
| GO:0030027 | Lamellipodium | IEA | cellular_component |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0051017 | Actin filament bundle assembly | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5783232704 | 0.0054431025 | 0.9999902473 | 0.1495489562 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8515989613 |
| GSE13712_SHEAR | Up | 0.1877225199 |
| GSE13712_STATIC | Up | 0.4623010279 |
| GSE19018 | Down | -0.1481736518 |
| GSE19899_A1 | Down | -0.9510161952 |
| GSE19899_A2 | Down | -0.7452309384 |
| PubMed_21979375_A1 | Down | -2.0480201294 |
| PubMed_21979375_A2 | Down | -1.1170816285 |
| GSE35957 | Up | 0.8049251132 |
| GSE36640 | Up | 0.7292508614 |
| GSE54402 | Down | -0.9603475803 |
| GSE9593 | Up | 0.6666153135 |
| GSE43922 | Down | -2.3935655860 |
| GSE24585 | Up | 0.0759860786 |
| GSE37065 | Down | -0.4009637795 |
| GSE28863_A1 | Down | -0.3060951288 |
| GSE28863_A2 | Up | 0.1030032150 |
| GSE28863_A3 | Up | 0.1300978764 |
| GSE28863_A4 | Down | -0.0701135676 |
| GSE48662 | Down | -0.1143213611 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT006889 | Immunofluorescence//Immunohistochemistry//qRT-PCR//Western blot | Functional MTI | 22869051 |
| hsa-miR-145-5p | MIMAT0000437 | MIRT006889 | Luciferase reporter assay | Functional MTI | 23355420 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047916 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
