HCSGD entry for DRG1
1. General information
| Official gene symbol | DRG1 |
|---|---|
| Entrez ID | 4733 |
| Gene full name | developmentally regulated GTP binding protein 1 |
| Other gene symbols | NEDD3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005844 | Polysome | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008134 | Transcription factor binding | TAS | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4153303446 | 0.2725810911 | 0.9999902473 | 0.9987342329 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5552977634 |
| GSE13712_SHEAR | Down | -0.2860332251 |
| GSE13712_STATIC | Down | -0.0208177976 |
| GSE19018 | Down | -0.7878009606 |
| GSE19899_A1 | Up | 0.4316839738 |
| GSE19899_A2 | Up | 0.0591938172 |
| PubMed_21979375_A1 | Up | 0.0638618615 |
| PubMed_21979375_A2 | Up | 0.1791998551 |
| GSE35957 | Down | -0.3484597282 |
| GSE36640 | Down | -0.0866500069 |
| GSE54402 | Up | 0.2534746159 |
| GSE9593 | Down | -0.0817444328 |
| GSE43922 | Up | 0.3561547938 |
| GSE24585 | Down | -0.2207906845 |
| GSE37065 | Down | -0.1129899477 |
| GSE28863_A1 | Down | -0.0826129621 |
| GSE28863_A2 | Down | -0.0388914118 |
| GSE28863_A3 | Down | -0.3540640975 |
| GSE28863_A4 | Up | 0.0990607139 |
| GSE48662 | Down | -0.3181249041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025534 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040302 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-605-5p | MIMAT0003273 | MIRT040480 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-455-5p | MIMAT0003150 | MIRT040743 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
