HCSGD entry for NDUFS8

1. General information

Official gene symbolNDUFS8
Entrez ID4728
Gene full nameNADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
Other gene symbolsCI-23k CI23KD TYKY
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003954NADH dehydrogenase activityIMPmolecular_function
GO:0005739MitochondrionIDA IEAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005747Mitochondrial respiratory chain complex IIDA IMP NAScellular_component
GO:0006120Mitochondrial electron transport, NADH to ubiquinoneNASbiological_process
GO:0006979Response to oxidative stressIDAbiological_process
GO:0008137NADH dehydrogenase (ubiquinone) activityIMP NASmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0016651Oxidoreductase activity, acting on NAD(P)HIEAmolecular_function
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0032981Mitochondrial respiratory chain complex I assemblyIMPbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051536Iron-sulfur cluster bindingIEAmolecular_function
GO:00515394 iron, 4 sulfur cluster bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99451424340.19853360050.99999024730.8617419030

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1457610618

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029672MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.