HCSGD entry for NDUFV1
1. General information
| Official gene symbol | NDUFV1 |
|---|---|
| Entrez ID | 4723 |
| Gene full name | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
| Other gene symbols | CI-51K CI51KD UQOR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005743 | Mitochondrial inner membrane | IEA NAS TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA IMP NAS | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | IC NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | IEA NAS | molecular_function |
| GO:0010181 | FMN binding | IEA | molecular_function |
| GO:0016651 | Oxidoreductase activity, acting on NAD(P)H | IEA | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051287 | NAD binding | IEA | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9600603055 | 0.2310283158 | 0.9999902473 | 0.9255549924 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0023100827 |
| GSE13712_SHEAR | Down | -0.1037859749 |
| GSE13712_STATIC | Down | -0.2121963525 |
| GSE19018 | Up | 0.2145063669 |
| GSE19899_A1 | Down | -0.2260268956 |
| GSE19899_A2 | Down | -0.0667164020 |
| PubMed_21979375_A1 | Up | 0.1201222859 |
| PubMed_21979375_A2 | Down | -0.1538554451 |
| GSE35957 | Up | 0.0208899198 |
| GSE36640 | Down | -0.1736323062 |
| GSE54402 | Down | -0.0068495379 |
| GSE9593 | Down | -0.0049948715 |
| GSE43922 | Up | 0.0006455480 |
| GSE24585 | Down | -0.0096346012 |
| GSE37065 | Down | -0.3796212588 |
| GSE28863_A1 | Up | 0.0906938506 |
| GSE28863_A2 | Down | -0.1130294979 |
| GSE28863_A3 | Down | -0.2706108662 |
| GSE28863_A4 | Up | 0.1126424993 |
| GSE48662 | Down | -0.3480695506 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041953 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
