HCSGD entry for NDUFB8
1. General information
| Official gene symbol | NDUFB8 |
|---|---|
| Entrez ID | 4714 |
| Gene full name | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| Other gene symbols | ASHI CI-ASHI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA NAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | IEA NAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9563308689 | 0.2490719995 | 0.9999902473 | 0.9590832554 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0573454232 |
| GSE13712_SHEAR | Down | -0.0231411360 |
| GSE13712_STATIC | Down | -0.1980634254 |
| GSE19018 | Up | 0.2543594914 |
| GSE19899_A1 | Down | -0.1290403913 |
| GSE19899_A2 | Up | 0.1861254750 |
| PubMed_21979375_A1 | Down | -0.1851806175 |
| PubMed_21979375_A2 | Up | 0.0015759230 |
| GSE35957 | Down | -0.4751599794 |
| GSE36640 | Up | 0.0030148220 |
| GSE54402 | Up | 0.1066539516 |
| GSE9593 | Down | -0.2255240091 |
| GSE43922 | Down | -0.0079756683 |
| GSE24585 | Down | -0.1650738989 |
| GSE37065 | Down | -0.1982201443 |
| GSE28863_A1 | Down | -0.0730189742 |
| GSE28863_A2 | Down | -0.1252343941 |
| GSE28863_A3 | Up | 0.1182355219 |
| GSE28863_A4 | Down | -0.0541960064 |
| GSE48662 | Down | -0.0272575420 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-505-5p | MIMAT0004776 | MIRT037965 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
