HCSGD entry for NDUFB3

1. General information

Official gene symbolNDUFB3
Entrez ID4709
Gene full nameNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
Other gene symbolsB12 CI-B12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005747Mitochondrial respiratory chain complex IIDA IEA NAScellular_component
GO:0006120Mitochondrial electron transport, NADH to ubiquinoneNASbiological_process
GO:0008137NADH dehydrogenase (ubiquinone) activityNASmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0022900Electron transport chainIEAbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58082922380.28937175640.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2087775389
GSE13712_SHEARDown-0.0733955643
GSE13712_STATICDown-0.1168449917
GSE19018Up0.0642023238
GSE19899_A1Up0.1653697067
GSE19899_A2Up0.0483516610
PubMed_21979375_A1Up0.0507822911
PubMed_21979375_A2Up0.2908788563
GSE35957Down-0.0110931664
GSE36640Up0.0149619355
GSE54402Up0.0803823112
GSE9593Down-0.2648983744
GSE43922Up0.1368443616
GSE24585Down-0.4968261873
GSE37065Up0.0807615759
GSE28863_A1Down-0.1701121704
GSE28863_A2Down-0.2524383437
GSE28863_A3Down-0.3512853136
GSE28863_A4Down-0.0636807423
GSE48662Up0.0886945483

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-18a-3pMIMAT0002891MIRT040891CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.