HCSGD entry for NDUFA9
1. General information
| Official gene symbol | NDUFA9 |
|---|---|
| Entrez ID | 4704 |
| Gene full name | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa |
| Other gene symbols | CC6 CI-39k CI39k NDUFS2L SDR22E1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | IEA | molecular_function |
| GO:0003954 | NADH dehydrogenase activity | IMP NAS | molecular_function |
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IDA | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | NAS | biological_process |
| GO:0006694 | Steroid biosynthetic process | IEA | biological_process |
| GO:0006814 | Sodium ion transport | NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0031966 | Mitochondrial membrane | IDA | cellular_component |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050662 | Coenzyme binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6654836822 | 0.0835706888 | 0.9999902473 | 0.5486814916 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4790829879 |
| GSE13712_SHEAR | Down | -0.2687630440 |
| GSE13712_STATIC | Down | -0.0527851701 |
| GSE19018 | Down | -0.5179631754 |
| GSE19899_A1 | Down | -0.7259977043 |
| GSE19899_A2 | Down | -0.2773840442 |
| PubMed_21979375_A1 | Up | 0.9753312876 |
| PubMed_21979375_A2 | Up | 0.1782563707 |
| GSE35957 | Down | -0.9138858495 |
| GSE36640 | Down | -0.4672695412 |
| GSE54402 | Up | 0.0839747073 |
| GSE9593 | Down | -0.3175906896 |
| GSE43922 | Down | -0.0651584591 |
| GSE24585 | Down | -0.2598220237 |
| GSE37065 | Up | 0.2379163259 |
| GSE28863_A1 | Up | 0.2869755149 |
| GSE28863_A2 | Up | 0.0411878926 |
| GSE28863_A3 | Down | -0.0319180812 |
| GSE28863_A4 | Up | 0.1349156068 |
| GSE48662 | Down | -0.3599058553 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031528 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048492 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
