HCSGD entry for NARS
1. General information
| Official gene symbol | NARS |
|---|---|
| Entrez ID | 4677 |
| Gene full name | asparaginyl-tRNA synthetase |
| Other gene symbols | ASNRS NARS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004816 | Asparagine-tRNA ligase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006421 | Asparaginyl-tRNA aminoacylation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2971326431 | 0.6329721591 | 0.9965377548 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2215378131 |
| GSE13712_SHEAR | Up | 0.0742827689 |
| GSE13712_STATIC | Up | 0.0637547641 |
| GSE19018 | Up | 0.0802851983 |
| GSE19899_A1 | Up | 0.3555772840 |
| GSE19899_A2 | Up | 0.2660057636 |
| PubMed_21979375_A1 | Up | 0.4750012628 |
| PubMed_21979375_A2 | Up | 0.0441240333 |
| GSE35957 | Up | 0.0767710187 |
| GSE36640 | Up | 0.0257776266 |
| GSE54402 | Down | -0.1062085989 |
| GSE9593 | Up | 0.2061021092 |
| GSE43922 | Up | 0.2577580812 |
| GSE24585 | Down | -0.4061233466 |
| GSE37065 | Down | -0.2322037461 |
| GSE28863_A1 | Down | -0.2719568095 |
| GSE28863_A2 | Down | -0.0394501596 |
| GSE28863_A3 | Down | -0.3968165856 |
| GSE28863_A4 | Up | 0.1103472950 |
| GSE48662 | Down | -0.1036955805 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001530 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT001530 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031806 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043484 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046695 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051384 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
