HCSGD entry for HNRNPM
1. General information
| Official gene symbol | HNRNPM |
|---|---|
| Entrez ID | 4670 |
| Gene full name | heterogeneous nuclear ribonucleoprotein M |
| Other gene symbols | CEAR HNRNPM4 HNRPM HNRPM4 HTGR1 NAGR1 hnRNP M |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000380 | Alternative mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC IEA TAS | biological_process |
| GO:0003723 | RNA binding | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016363 | Nuclear matrix | IDA | cellular_component |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0042382 | Paraspeckles | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9441302116 | 0.2165954219 | 0.9999902473 | 0.8961031279 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0072234630 |
| GSE13712_SHEAR | Up | 0.1746705463 |
| GSE13712_STATIC | Up | 0.0793503354 |
| GSE19018 | Down | -0.2574017703 |
| GSE19899_A1 | Down | -0.1618835828 |
| GSE19899_A2 | Down | -0.0744666872 |
| PubMed_21979375_A1 | Down | -0.0672145939 |
| PubMed_21979375_A2 | Down | -0.1886405776 |
| GSE35957 | Down | -0.2645052900 |
| GSE36640 | Down | -0.4370624001 |
| GSE54402 | Up | 0.1333622424 |
| GSE9593 | Down | -0.2639980108 |
| GSE43922 | Down | -0.2484994638 |
| GSE24585 | Down | -0.1081918426 |
| GSE37065 | Down | -0.1123016990 |
| GSE28863_A1 | Down | -0.0010924667 |
| GSE28863_A2 | Up | 0.0392210048 |
| GSE28863_A3 | Up | 0.2369217119 |
| GSE28863_A4 | Up | 0.0644049082 |
| GSE48662 | Down | -0.0245110995 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005120 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029321 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7f-1-3p | MIMAT0004486 | MIRT038991 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039993 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040906 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041425 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042112 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043473 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045805 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046439 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047057 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048765 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049361 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-29a-3p | MIMAT0000086 | MIRT049986 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
