HCSGD entry for NAGLU


1. General information

Official gene symbolNAGLU
Entrez ID4669
Gene full nameN-acetylglucosaminidase, alpha
Other gene symbolsMPS-IIIB MPS3B NAG UFHSD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004561Alpha-N-acetylglucosaminidase activityIEAmolecular_function
GO:0005764LysosomeTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006027Glycosaminoglycan catabolic processTASbiological_process
GO:0007040Lysosome organizationIEAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0021680Cerebellar Purkinje cell layer developmentIEAbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0043202Lysosomal lumenTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045475Locomotor rhythmIEAbiological_process
GO:0046548Retinal rod cell developmentIEAbiological_process
GO:0060119Inner ear receptor cell developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53853067130.57046127810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0586708174
GSE13712_SHEARDown-0.1350706427
GSE13712_STATICDown-0.2609068042
GSE19018Up0.2349423572
GSE19899_A1Down-0.3383565454
GSE19899_A2Down-0.0047980411
PubMed_21979375_A1Down-0.1626429905
PubMed_21979375_A2Up0.2463520043
GSE35957Up0.0158906423
GSE36640Up0.3582889441
GSE54402Down-0.0680977298
GSE9593Up0.3821479407
GSE43922Down-0.0001749351
GSE24585Down-0.1900020918
GSE37065Up0.0628202312
GSE28863_A1Down-0.0497862455
GSE28863_A2Up0.2805050951
GSE28863_A3Down-0.0949337397
GSE28863_A4Down-0.0010161401
GSE48662Up0.3584076078

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

N-Acetyl-D-glucosamineDB00141 NUTR00040

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.