HCSGD entry for PPP1R12A
1. General information
| Official gene symbol | PPP1R12A |
|---|---|
| Entrez ID | 4659 |
| Gene full name | protein phosphatase 1, regulatory subunit 12A |
| Other gene symbols | M130 MBS MYPT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000776 | Kinetochore | IDA | cellular_component |
| GO:0004857 | Enzyme inhibitor activity | IDA | molecular_function |
| GO:0004871 | Signal transducer activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IEA IMP | biological_process |
| GO:0007067 | Mitosis | IMP | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0019208 | Phosphatase regulator activity | IDA IMP | molecular_function |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0030155 | Regulation of cell adhesion | IDA | biological_process |
| GO:0035507 | Regulation of myosin-light-chain-phosphatase activity | IDA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | IDA | biological_process |
| GO:0043292 | Contractile fiber | IDA | cellular_component |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046822 | Regulation of nucleocytoplasmic transport | IEA | biological_process |
| GO:0051297 | Centrosome organization | IMP | biological_process |
| GO:0071889 | 14-3-3 protein binding | IDA | molecular_function |
| GO:0072357 | PTW/PP1 phosphatase complex | IDA | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9172914023 | 0.0199727442 | 0.9999902473 | 0.2749490586 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1686677757 |
| GSE13712_SHEAR | Down | -0.0172421650 |
| GSE13712_STATIC | Down | -0.0503258775 |
| GSE19018 | Up | 0.0431761035 |
| GSE19899_A1 | Down | -0.4076367809 |
| GSE19899_A2 | Down | -0.9140258813 |
| PubMed_21979375_A1 | Down | -0.3799495033 |
| PubMed_21979375_A2 | Down | -0.6342002411 |
| GSE35957 | Down | -0.1615879524 |
| GSE36640 | Down | -0.4079991953 |
| GSE54402 | Down | -0.2542584396 |
| GSE9593 | Up | 0.0042546973 |
| GSE43922 | Down | -0.4214669436 |
| GSE24585 | Up | 0.4091888261 |
| GSE37065 | Down | -0.0207915796 |
| GSE28863_A1 | Up | 0.3810095321 |
| GSE28863_A2 | Up | 0.0889948341 |
| GSE28863_A3 | Down | -0.3164258869 |
| GSE28863_A4 | Up | 0.0644977406 |
| GSE48662 | Down | -0.3102092816 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024772 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026571 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027917 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028611 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038793 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047621 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047894 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
