HCSGD entry for MYO7A

1. General information

Official gene symbolMYO7A
Entrez ID4647
Gene full namemyosin VIIA
Other gene symbolsDFNA11 DFNB2 MYOVIIA MYU7A NSRD2 USH1B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000146Microfilament motor activityIDAmolecular_function
GO:0001750Photoreceptor outer segmentIDAcellular_component
GO:0001845Phagolysosome assemblyIEAbiological_process
GO:0001917Photoreceptor inner segmentIDAcellular_component
GO:0003774Motor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIMPmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0006886Intracellular protein transportIEAbiological_process
GO:0007040Lysosome organizationIDAbiological_process
GO:0007601Visual perceptionIMPbiological_process
GO:0007605Sensory perception of soundIMPbiological_process
GO:0008152Metabolic processIDAbiological_process
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016459Myosin complexIEAcellular_component
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030048Actin filament-based movementIDAbiological_process
GO:0030898Actin-dependent ATPase activityIEAmolecular_function
GO:0031477Myosin VII complexIEAcellular_component
GO:0032391Photoreceptor connecting ciliumIEAcellular_component
GO:0032420StereociliumIEAcellular_component
GO:0042462Eye photoreceptor cell developmentICbiological_process
GO:0042470MelanosomeIEAcellular_component
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043531ADP bindingIEAmolecular_function
GO:0045202SynapseIDAcellular_component
GO:0046983Protein dimerization activityRCAmolecular_function
GO:0048563Post-embryonic organ morphogenesisIEAbiological_process
GO:0050953Sensory perception of light stimulusIMPbiological_process
GO:0050957EquilibrioceptionIMPbiological_process
GO:0051015Actin filament bindingIDAmolecular_function
GO:0051904Pigment granule transportIEAbiological_process
GO:0060088Auditory receptor cell stereocilium organizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72001957750.75987099650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0021746584
GSE13712_SHEARDown-0.4797786180
GSE13712_STATICDown-0.4680513262
GSE19018Up0.0703883968
GSE19899_A1Up0.0579213240
GSE19899_A2Up0.0741958014
PubMed_21979375_A1Up0.0903049291
PubMed_21979375_A2Down-0.0048494453
GSE35957Up0.1192449941
GSE36640Down-0.0004981311
GSE54402Up0.0158619060
GSE9593Down-0.0095632125
GSE43922Up0.0584975900
GSE24585Up0.0130032713
GSE37065Down-0.0498661113
GSE28863_A1Up0.0031557286
GSE28863_A2Down-0.0181047667
GSE28863_A3Up0.3800679238
GSE28863_A4Up0.1671812524
GSE48662Up0.0035463744

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018231MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.