HCSGD entry for MYH4

1. General information

Official gene symbolMYH4
Entrez ID4622
Gene full namemyosin, heavy chain 4, skeletal muscle
Other gene symbolsMYH2B MyHC-2B MyHC-IIb
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000146Microfilament motor activityNASmolecular_function
GO:0003725Double-stranded RNA bindingIDAmolecular_function
GO:0003779Actin bindingIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005859Muscle myosin complexNAScellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006936Muscle contractionIDAbiological_process
GO:0008152Metabolic processNASbiological_process
GO:0008307Structural constituent of muscleNASmolecular_function
GO:0014823Response to activityIEAbiological_process
GO:0030016MyofibrilIDAcellular_component
GO:0030017SarcomereNAScellular_component
GO:0030048Actin filament-based movementNASbiological_process
GO:0030049Muscle filament slidingNASbiological_process
GO:0032982Myosin filamentIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55635923410.79201396220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1967996315
GSE13712_SHEARDown-0.0356621200
GSE13712_STATICUp0.0070913890
GSE19018Up0.1601484458
GSE19899_A1Up0.1647604701
GSE19899_A2Up0.0396616624
PubMed_21979375_A1Up0.0057392374
PubMed_21979375_A2Down-0.1506359963
GSE35957Up0.0690061766
GSE36640Up0.0828140412
GSE54402Up0.1419187887
GSE9593Down-0.1894788274
GSE43922Up0.0169176400
GSE24585Up0.1575289536
GSE37065Down-0.0336209765
GSE28863_A1Down-0.1027534290
GSE28863_A2Down-0.2949492155
GSE28863_A3Up0.3034791922
GSE28863_A4Up0.0307588963
GSE48662Down-0.0106921183

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-23a-3pMIMAT0000078MIRT006909Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI22771720
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.