HCSGD entry for MUSK

1. General information

Official gene symbolMUSK
Entrez ID4593
Gene full namemuscle, skeletal, receptor tyrosine kinase
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001934Positive regulation of protein phosphorylationISSbiological_process
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004713Protein tyrosine kinase activityISSmolecular_function
GO:0004714Transmembrane receptor protein tyrosine kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneISScellular_component
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayTASbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007528Neuromuscular junction developmentISSbiological_process
GO:0007613MemoryISSbiological_process
GO:0008582Regulation of synaptic growth at neuromuscular junctionISSbiological_process
GO:0010628Positive regulation of gene expressionISSbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationISSbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030154Cell differentiationIEAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0031594Neuromuscular junctionISScellular_component
GO:0043235Receptor complexIDAcellular_component
GO:0043525Positive regulation of neuron apoptotic processIEAbiological_process
GO:0045211Postsynaptic membraneISScellular_component
GO:0046777Protein autophosphorylationISSbiological_process
GO:0071340Skeletal muscle acetylcholine-gated channel clusteringISSbiological_process
GO:2000541Positive regulation of protein geranylgeranylationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41389970750.96498387220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0843556828
GSE13712_SHEARDown-0.0760800608
GSE13712_STATICUp0.0044656392
GSE19018Up0.1392800134
GSE19899_A1Up0.0352991034
GSE19899_A2Up0.0956850880
PubMed_21979375_A1Up0.3117168062
PubMed_21979375_A2Up0.1499611639
GSE35957Up0.0615887305
GSE36640Up0.1390271220
GSE54402Down-0.0713493554
GSE9593Down-0.0732585900
GSE43922Up0.0165754296
GSE24585Up0.1415156330
GSE37065Up0.1872044451
GSE28863_A1Down-0.0021605359
GSE28863_A2Up0.1400470296
GSE28863_A3Up0.1573284533
GSE28863_A4Up0.0573766964
GSE48662Up0.1279209885

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.