HCSGD entry for MTTP

1. General information

Official gene symbolMTTP
Entrez ID4547
Gene full namemicrosomal triglyceride transfer protein
Other gene symbolsABL MTP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005319Lipid transporter activityIEA TASmolecular_function
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005791Rough endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0006497Protein lipidationIEAbiological_process
GO:0006629Lipid metabolic processTASbiological_process
GO:0006641Triglyceride metabolic processIEAbiological_process
GO:0008289Lipid bindingIEAmolecular_function
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0031526Brush border membraneIEAcellular_component
GO:0031528Microvillus membraneIEAcellular_component
GO:0031988Membrane-bounded vesicleIEAcellular_component
GO:0034185Apolipoprotein bindingIEAmolecular_function
GO:0042157Lipoprotein metabolic processTASbiological_process
GO:0042632Cholesterol homeostasisIEAbiological_process
GO:0042953Lipoprotein transportIEAbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0051592Response to calcium ionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75321466130.77431709280.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0307064949
GSE13712_SHEARDown-0.1820793039
GSE13712_STATICDown-0.0598393058
GSE19018Up0.0208781092
GSE19899_A1Up0.0144424427
GSE19899_A2Down-0.2053377459
PubMed_21979375_A1Up0.2610087901
PubMed_21979375_A2Down-0.0195165619
GSE35957Down-0.0169566931
GSE36640Down-0.0479686322
GSE54402Up0.0482838769
GSE9593Up0.0255168839
GSE43922Up0.0153269426
GSE24585Up0.2453669053
GSE37065Up0.0036619276
GSE28863_A1Down-0.0120976093
GSE28863_A2Up0.1421863757
GSE28863_A3Up0.1711233046
GSE28863_A4Up0.0163737224
GSE48662Down-0.0630067528

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

HesperetinDB01094 APRD00117
ImplitapideDB04852 -
LomitapideDB08827 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.