HCSGD entry for MTM1

1. General information

Official gene symbolMTM1
Entrez ID4534
Gene full namemyotubularin 1
Other gene symbolsCNM MTMX XLMTM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIDAcellular_component
GO:0004438Phosphatidylinositol-3-phosphatase activityIDAmolecular_function
GO:0004721Phosphoprotein phosphatase activityIDAmolecular_function
GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005770Late endosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006470Protein dephosphorylationIDAbiological_process
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processTASbiological_process
GO:0008333Endosome to lysosome transportIDAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0019215Intermediate filament bindingIDAmolecular_function
GO:0030175FilopodiumIDAcellular_component
GO:0031674I bandIEAcellular_component
GO:0035091Phosphatidylinositol bindingIDAmolecular_function
GO:0044088Regulation of vacuole organizationIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045109Intermediate filament organizationIMPbiological_process
GO:0046716Muscle cell cellular homeostasisIEAbiological_process
GO:0046856Phosphatidylinositol dephosphorylationIDAbiological_process
GO:0048311Mitochondrion distributionIEA IMPbiological_process
GO:0052629Phosphatidylinositol-3,5-bisphosphate 3-phosphatase activityIDAmolecular_function
GO:0070584Mitochondrion morphogenesisIDA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07790178180.81572318300.58871653751.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0102868232
GSE13712_SHEARDown-0.7972162532
GSE13712_STATICDown-0.1982830324
GSE19018Up0.1579603459
GSE19899_A1Up0.0792766584
GSE19899_A2Up0.5895624899
PubMed_21979375_A1Up1.4579059930
PubMed_21979375_A2Up0.5037227965
GSE35957Up0.0621929885
GSE36640Up0.6898316288
GSE54402Up0.1136144970
GSE9593Up0.1890961268
GSE43922Up0.0470688657
GSE24585Up0.1006950997
GSE37065Up0.2968249605
GSE28863_A1Up0.1775003696
GSE28863_A2Up0.2843309160
GSE28863_A3Down-0.0552039960
GSE28863_A4Up0.0505829119
GSE48662Down-0.7017961491

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.