HCSGD entry for MTIF2
1. General information
| Official gene symbol | MTIF2 |
|---|---|
| Entrez ID | 4528 |
| Gene full name | mitochondrial translational initiation factor 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001732 | Formation of translation initiation complex | ISS | biological_process |
| GO:0003743 | Translation initiation factor activity | IEA | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IC IDA IEA | cellular_component |
| GO:0006446 | Regulation of translational initiation | ISS | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | ISS | molecular_function |
| GO:0032790 | Ribosome disassembly | ISS | biological_process |
| GO:0043024 | Ribosomal small subunit binding | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9331256525 | 0.0505527791 | 0.9999902473 | 0.4214759899 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2879015215 |
| GSE13712_SHEAR | Up | 0.2562704256 |
| GSE13712_STATIC | Up | 0.1265537553 |
| GSE19018 | Down | -0.3912408340 |
| GSE19899_A1 | Down | -0.0865182929 |
| GSE19899_A2 | Up | 0.1270548669 |
| PubMed_21979375_A1 | Up | 0.1746411350 |
| PubMed_21979375_A2 | Up | 0.0462677563 |
| GSE35957 | Down | -0.3758049496 |
| GSE36640 | Down | -0.6343586673 |
| GSE54402 | Down | -0.1390907708 |
| GSE9593 | Down | -0.3682157784 |
| GSE43922 | Down | -0.0153329263 |
| GSE24585 | Down | -0.8387346065 |
| GSE37065 | Down | -0.0483616931 |
| GSE28863_A1 | Down | -0.0189310400 |
| GSE28863_A2 | Up | 0.0400623758 |
| GSE28863_A3 | Down | -0.7271538148 |
| GSE28863_A4 | Down | -0.0638373771 |
| GSE48662 | Down | -0.3067559048 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041908 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
