HCSGD entry for MT1X
1. General information
| Official gene symbol | MT1X |
|---|---|
| Entrez ID | 4501 |
| Gene full name | metallothionein 1X |
| Other gene symbols | MT-1l MT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | ISS | molecular_function |
| GO:0010038 | Response to metal ion | TAS | biological_process |
| GO:0036018 | Cellular response to erythropoietin | IEP | biological_process |
| GO:0045926 | Negative regulation of growth | ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA TAS | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | ISS | cellular_component |
| GO:0071276 | Cellular response to cadmium ion | IEP | biological_process |
| GO:0071294 | Cellular response to zinc ion | IEP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0003667300 | 0.8903150032 | 0.0516187166 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.1367392209 |
| GSE13712_SHEAR | Up | 2.4372553629 |
| GSE13712_STATIC | Up | 0.9667229005 |
| GSE19018 | Up | 1.0642923772 |
| GSE19899_A1 | Up | 0.9590827695 |
| GSE19899_A2 | Up | 0.8142362459 |
| PubMed_21979375_A1 | Up | 1.1251424712 |
| PubMed_21979375_A2 | Up | 0.6227138798 |
| GSE35957 | Down | -1.4210408885 |
| GSE36640 | Up | 0.3452288051 |
| GSE54402 | Up | 1.2565626596 |
| GSE9593 | Up | 0.5625835458 |
| GSE43922 | Up | 1.0925352962 |
| GSE24585 | Down | -0.3337435659 |
| GSE37065 | Up | 0.3231245136 |
| GSE28863_A1 | Down | -0.0852449406 |
| GSE28863_A2 | Down | -0.0958163690 |
| GSE28863_A3 | Up | 0.6412485824 |
| GSE28863_A4 | Down | -0.1006305671 |
| GSE48662 | Down | -0.4766788813 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026466 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
