HCSGD entry for MSH4


1. General information

Official gene symbolMSH4
Entrez ID4438
Gene full namemutS homolog 4 (E. coli)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000710Meiotic mismatch repairIRDbiological_process
GO:0000795Synaptonemal complexIBAcellular_component
GO:0001541Ovarian follicle developmentIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0003684Damaged DNA bindingIRDmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusTAScellular_component
GO:0006200ATP catabolic processIBAbiological_process
GO:0007131Reciprocal meiotic recombinationIBAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0007292Female gamete generationIEAbiological_process
GO:0008094DNA-dependent ATPase activityIBAmolecular_function
GO:0030983Mismatched DNA bindingIBAmolecular_function
GO:0032300Mismatch repair complexIRDcellular_component
GO:0045143Homologous chromosome segregationIBAbiological_process
GO:0051026Chiasma assemblyIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52834683330.79300472630.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2467702718
GSE13712_SHEARDown-0.0844617210
GSE13712_STATICDown-0.0034088373
GSE19018Down-0.0865439332
GSE19899_A1Up0.1416357836
GSE19899_A2Up0.0000318051
PubMed_21979375_A1Up0.5554385933
PubMed_21979375_A2Down-0.0595052644
GSE35957Up0.0605441032
GSE36640Up0.3006931289
GSE54402Up0.1915677513
GSE9593Down-0.2991672145
GSE43922Up0.0198779802
GSE24585Down-0.3614242651
GSE37065Up0.0429046137
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0446457437

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.