HCSGD entry for MYO1B
1. General information
| Official gene symbol | MYO1B |
|---|---|
| Entrez ID | 4430 |
| Gene full name | myosin IB |
| Other gene symbols | myr1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000146 | Microfilament motor activity | ISS | molecular_function |
| GO:0003774 | Motor activity | IEA | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA ISS | molecular_function |
| GO:0005546 | Phosphatidylinositol-4,5-bisphosphate binding | ISS | molecular_function |
| GO:0005547 | Phosphatidylinositol-3,4,5-trisphosphate binding | ISS | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0005903 | Brush border | ISS | cellular_component |
| GO:0008152 | Metabolic process | ISS | biological_process |
| GO:0016459 | Myosin complex | IEA | cellular_component |
| GO:0030048 | Actin filament-based movement | ISS | biological_process |
| GO:0030175 | Filopodium | ISS | cellular_component |
| GO:0051017 | Actin filament bundle assembly | ISS | biological_process |
| GO:0071944 | Cell periphery | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1414112534 | 0.4489198549 | 0.7554466410 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1383772294 |
| GSE13712_SHEAR | Up | 0.1715774868 |
| GSE13712_STATIC | Up | 0.0604842672 |
| GSE19018 | Down | -0.2922567218 |
| GSE19899_A1 | Up | 0.4351125573 |
| GSE19899_A2 | Up | 0.2048115308 |
| PubMed_21979375_A1 | Up | 0.4771189153 |
| PubMed_21979375_A2 | Up | 0.3624881579 |
| GSE35957 | Up | 0.8238137215 |
| GSE36640 | Down | -0.1595313641 |
| GSE54402 | Up | 0.2079858010 |
| GSE9593 | Up | 0.3628878571 |
| GSE43922 | Up | 0.0630004594 |
| GSE24585 | Down | -0.1008651536 |
| GSE37065 | Down | -0.2505093039 |
| GSE28863_A1 | Down | -0.4537104430 |
| GSE28863_A2 | Up | 0.1683953702 |
| GSE28863_A3 | Down | -0.5269131803 |
| GSE28863_A4 | Down | -0.2844429767 |
| GSE48662 | Up | 0.2771717591 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023559 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023559 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043983 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
