HCSGD entry for KLK12
1. General information
| Official gene symbol | KLK12 |
|---|---|
| Entrez ID | 43849 |
| Gene full name | kallikrein-related peptidase 12 |
| Other gene symbols | KLK-L5 KLKL5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA NAS | molecular_function |
| GO:0005615 | Extracellular space | NAS | cellular_component |
| GO:0006508 | Proteolysis | IDA IEA | biological_process |
| GO:0008233 | Peptidase activity | IDA | molecular_function |
| GO:0008236 | Serine-type peptidase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7136311690 | 0.8985727024 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0422401496 |
| GSE13712_SHEAR | Down | -0.0345797675 |
| GSE13712_STATIC | Up | 0.0869474472 |
| GSE19018 | Up | 0.0839849594 |
| GSE19899_A1 | Down | -0.0212194228 |
| GSE19899_A2 | Up | 0.1262110625 |
| PubMed_21979375_A1 | Up | 0.0454540023 |
| PubMed_21979375_A2 | Down | -0.0363863265 |
| GSE35957 | Up | 0.0688249810 |
| GSE36640 | Up | 0.0294524885 |
| GSE54402 | Down | -0.0191672320 |
| GSE9593 | Up | 0.0071066266 |
| GSE43922 | Up | 0.0140074274 |
| GSE24585 | Up | 0.0493314800 |
| GSE37065 | Down | -0.0185901529 |
| GSE28863_A1 | Down | -0.0550008654 |
| GSE28863_A2 | Down | -0.0370068402 |
| GSE28863_A3 | Up | 0.1708447904 |
| GSE28863_A4 | Up | 0.1508741000 |
| GSE48662 | Up | 0.1235016462 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023672 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
