HCSGD entry for MPG
1. General information
| Official gene symbol | MPG |
|---|---|
| Entrez ID | 4350 |
| Gene full name | N-methylpurine-DNA glycosylase |
| Other gene symbols | AAG ADPG APNG CRA36.1 MDG Mid1 PIG11 PIG16 anpg |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003684 | Damaged DNA binding | TAS | molecular_function |
| GO:0003905 | Alkylbase DNA N-glycosylase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006284 | Base-excision repair | IEA TAS | biological_process |
| GO:0006285 | Base-excision repair, AP site formation | TAS | biological_process |
| GO:0006307 | DNA dealkylation involved in DNA repair | TAS | biological_process |
| GO:0008725 | DNA-3-methyladenine glycosylase activity | IEA | molecular_function |
| GO:0043916 | DNA-7-methylguanine glycosylase activity | IEA | molecular_function |
| GO:0045007 | Depurination | TAS | biological_process |
| GO:0052821 | DNA-7-methyladenine glycosylase activity | IEA | molecular_function |
| GO:0052822 | DNA-3-methylguanine glycosylase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0760653623 | 0.9360070248 | 0.5832200349 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1641059107 |
| GSE13712_SHEAR | Up | 0.0973839916 |
| GSE13712_STATIC | Up | 0.0668626914 |
| GSE19018 | Up | 0.2395489933 |
| GSE19899_A1 | Up | 0.1752158632 |
| GSE19899_A2 | Up | 0.6620143321 |
| PubMed_21979375_A1 | Up | 1.2244858498 |
| PubMed_21979375_A2 | Up | 0.3361085934 |
| GSE35957 | Down | -0.4021002338 |
| GSE36640 | Up | 0.0977908876 |
| GSE54402 | Up | 0.4711053704 |
| GSE9593 | Down | -0.0305400560 |
| GSE43922 | Up | 0.1458780695 |
| GSE24585 | Up | 0.0674057972 |
| GSE37065 | Down | -0.0917675774 |
| GSE28863_A1 | Down | -0.0212391954 |
| GSE28863_A2 | Down | -0.0840700277 |
| GSE28863_A3 | Up | 0.0234503472 |
| GSE28863_A4 | Up | 0.0789115746 |
| GSE48662 | Down | -0.0352039686 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032215 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048882 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049590 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
