HCSGD entry for ASL
1. General information
| Official gene symbol | ASL |
|---|---|
| Entrez ID | 435 |
| Gene full name | argininosuccinate lyase |
| Other gene symbols | ASAL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000050 | Urea cycle | IEA TAS | biological_process |
| GO:0004056 | Argininosuccinate lyase activity | EXP IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006475 | Internal protein amino acid acetylation | IDA | biological_process |
| GO:0006527 | Arginine catabolic process | TAS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042450 | Arginine biosynthetic process via ornithine | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3044370959 | 0.1608269899 | 0.9999902473 | 0.7740581140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0357810581 |
| GSE13712_SHEAR | Up | 0.1325344631 |
| GSE13712_STATIC | Up | 0.0177796350 |
| GSE19018 | Up | 0.1368584452 |
| GSE19899_A1 | Down | -0.1890040577 |
| GSE19899_A2 | Down | -0.1171132315 |
| PubMed_21979375_A1 | Up | 0.8992633915 |
| PubMed_21979375_A2 | Down | -0.5803554933 |
| GSE35957 | Up | 0.3336739734 |
| GSE36640 | Up | 0.6702189661 |
| GSE54402 | Up | 0.0031053222 |
| GSE9593 | Down | -0.4006150946 |
| GSE43922 | Down | -0.0080782633 |
| GSE24585 | Up | 0.6754599947 |
| GSE37065 | Down | -0.3138041605 |
| GSE28863_A1 | Down | -0.1451561063 |
| GSE28863_A2 | Down | -0.0899733145 |
| GSE28863_A3 | Down | -0.4119377452 |
| GSE28863_A4 | Down | -0.1113282231 |
| GSE48662 | Down | -0.1449370197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Arginine | DB00125 | NUTR00014 |
| Argininosuccinate | DB02267 | EXPT00565 |
| 2-(N-Morpholino)-Ethanesulfonic Acid | DB03814 | EXPT02154 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
