HCSGD entry for MOCS1


1. General information

Official gene symbolMOCS1
Entrez ID4337
Gene full namemolybdenum cofactor synthesis 1
Other gene symbolsMIG11 MOCOD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005634NucleusNAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006777Mo-molybdopterin cofactor biosynthetic processIDA IMP TASbiological_process
GO:0016829Lyase activityIEAmolecular_function
GO:0019008Molybdopterin synthase complexIEAcellular_component
GO:0032324Molybdopterin cofactor biosynthetic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:00515394 iron, 4 sulfur cluster bindingIDA IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47196538890.62661303900.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0349166592
GSE13712_SHEARUp0.0422878556
GSE13712_STATICUp0.0899369621
GSE19018Up0.0539616157
GSE19899_A1Down-0.0528178179
GSE19899_A2Up0.2510048942
PubMed_21979375_A1Up0.1670720068
PubMed_21979375_A2Up0.3951766156
GSE35957Down-0.3774410657
GSE36640Up0.0499511023
GSE54402Down-0.4511683791
GSE9593Down-0.1936991023
GSE43922Up0.0498191638
GSE24585Down-0.0836528442
GSE37065Down-0.1474783855
GSE28863_A1Down-0.0059364851
GSE28863_A2Down-0.0904974850
GSE28863_A3Up0.3137758922
GSE28863_A4Up0.0575817284
GSE48662Up0.3247467673

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT044828CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.