HCSGD entry for MNDA
1. General information
| Official gene symbol | MNDA |
|---|---|
| Entrez ID | 4332 |
| Gene full name | myeloid cell nuclear differentiation antigen |
| Other gene symbols | PYHIN3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006968 | Cellular defense response | TAS | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IMP | biological_process |
| GO:0030889 | Negative regulation of B cell proliferation | IMP | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0050853 | B cell receptor signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8193705748 | 0.5628388435 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2132833432 |
| GSE13712_SHEAR | Down | -0.2775905064 |
| GSE13712_STATIC | Down | -0.0551235626 |
| GSE19018 | Up | 0.0085356778 |
| GSE19899_A1 | Up | 0.0666635009 |
| GSE19899_A2 | Up | 0.0440133075 |
| PubMed_21979375_A1 | Down | -0.0523558039 |
| PubMed_21979375_A2 | Up | 0.0245452513 |
| GSE35957 | Down | -0.1407556490 |
| GSE36640 | Up | 0.1389684751 |
| GSE54402 | Up | 0.0159104690 |
| GSE9593 | Down | -0.2523904100 |
| GSE43922 | Up | 0.0201203432 |
| GSE24585 | Up | 0.1743494032 |
| GSE37065 | Up | 0.0060074141 |
| GSE28863_A1 | Down | -0.0562707810 |
| GSE28863_A2 | Down | -0.1857307414 |
| GSE28863_A3 | Up | 0.0676483148 |
| GSE28863_A4 | Down | -0.1031033734 |
| GSE48662 | Up | 0.0014662600 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029540 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17981573 | The family includes structurally and functionally-related mouse (for example, p202, p203, and p204 proteins) and human (for example, MNDA, AIM2, and IFIX) proteins |
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